Concepts in Cytomics G.Valet former: Cell Biochemistry Group Max-Planck-Institut für Biochemie, Martinsried

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The goal of this concept display is to advance the scientific discussion on the potential of cytomics in basic as well as in clinical research with regard to predictive medicine, biomolecular diagnostics and consensus development at an interdisciplinary level.
- Disease related processes can be determined at the cellular level by cytometric methods since diseases are caused by molecular changes in cellular systems or organs. This permits disease detection (diagnosis) as well as the prediction on future disease progression in individual patients.
- Clinical cytometry addresses frequently immunological and hematological issues by cellular immunophenotyping as major methodology e.g. in leukemia classification, hematopoietic stem cell or kidney transplantation and HIV infection monitoring.
- Multiparameter measurements of cell functions in conjunction with antibody binding and DNA determinations are important for the detection and follow-up of fast developing clinical processes like infectious, allergic, thrombotic or rheumatoid affections as well as for the control of therapy.

1. General Concepts

   Towards a human cytome project (PPT, 181, 2, 3, 4, 175, 170, definitions, cytomics references)
   Human Cytome Project (2003)
   Human Cytome Project, Cytomics & Systems Biology
   Predictive Medicine by Cytomics
   Cytomics, a Biomedical Key Discipline
   Cytome & Cytomics Definitions
   Toponomics
   Digital Microscopy
   Analytical Cellular Pathology: Presence and Future
   Microorganisms, Plant Cells
   Early Concepts in Flow Cytometry
   Concepts & Developments in Flow Cytometry & Cytomics at Martinsried

2. Clinical Cytomics

   Cytomics, from Prognostic to Predictive Medicine
   Cytomics, a Practical Approach
   Automated Disease Classification
   Affordable HIV Immunophenotyping
   Cellular Diagnosis in Vascular Medicine

3. Organisational Concepts

   Foundation: European Working Group on Clinical Cell Analysis (EWGCCA)
   Discussion: Europ.Fed.of Cytometric Societies

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