![]() |
6th ESACP Congress, Heidelberg, April 7-11, 1999 |
A081
In patients with ovarian cancer, parameters such as FIGO staging,
histopathologic type and grading are of important prognostic value.
The last decade DNA ploidy distribution has also become an important
prognostic tool. In the present study we have assessed about 250 cases
of ovarian cancer Stage I, taken from patients treated at the Norwegian
Radium hospital from 1982 to 1989, with both flow cytometry (FCM) and
image cytometry (ICM). All tumors were staged according to FIGO and
histologically verified by light microscopy of hematoxylin-eosin stained
sections. Histological samples were sliced into 50 micrometers (FCM) and
100 micrometers (ICM) sections, deparaffinized, and stained with
ethidiumbromide and feulgen, respectively. Preliminary data suggests
approximately 80 % correlation between ploidy and prognosis, and the
correlation between FCM and ICM is about 85 %. These data will be
presented in detail on the ESACP congress.
PROGNOSTIC SIGNIFICANCE AND COMPARISON BETWEEN IMAGE CYTOMETRY AND
FLOW CYTOMETRY IN DNA PLOIDY DISTRIBUTION IN EPITHELIAL OVARIAN CANCER
STAGE 1
Kildal W 1, Kristensen GB 2, Abeler VM 1, Pettersen EO 1
Danielsen HE 1
1) Depts.Pathology and 2) Gynecologic Oncology, The Norwegian Radium
Hospital, Montebello Oslo, Norway